Vitamin B12
What is vitamin B12? It's a water-soluble vitamin, also called cobalamin.
It's an essential nutrient that can promote heart health by contributing to normal homocysteine levels and supporting brain health and cognition.
The bioactive forms of vitamin B12
Methylcobalamin is the most well known bioactive form of vitamin B12. However the other essential active form is adenosylcobalamin, which has unique properties.
Adenosylcobalamin can protect neurons and prevent a decline in levels of the critical neurotransmitter, dopamine.
- The methylcobalamin form is essential for proper DNA synthesis, red blood cell formation, cell growth, and more.
- The adenosylcobalamin form is active in the mitochondria, the powerhouses of the cells.
- A combination of both bioactive forms of vitamin B12 offers protection for aging brain cells.
B12 deficiency
Those who have a deficiency of B12 tend to suffer digestive disturbances, anemia and blood disorders, and fatigue. Deficiency can also affect the peripheral nerves.
In later stages, it may target the spinal cord. All this can lead to impaired mental function, often manifesting as slower thinking, attention deficits, and memory lapses.
A preclinical study has shown it has the ability to protect brain neurons and to prevent a decline of the neurotransmitter dopamine in animal models.
Vegans, vegetarians, and the aging often develop vitamin B12 deficiencies. Oral intake of both active forms of vitamin B12 can support brain and body health.
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